Football World Cup Betting Odds, Best Bets, & Prediction for the USA vs. Wales

The USMNT is favored to start their World Cup campaign with a victory over a team making their first participation in the competition since 1958.

After missing out on the 2018 World Cup, the United States will make its World Cup debut in 2022, when they face Wales in Group B. This match will take place on Monday, November 21, at 2 p.m. ET at Al Rayyan Stadium.

The United States was one of four teams to qualify for CONCACAF after being ranked in the top five of the group in FIFA’s world rankings.

Wales qualified for the World Cup for the second time in their history after winning the UEFA Path A playoff.

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Group B also features England and Iran, with England predicted to emerge as the group champion. The victor of this match will almost certainly be the second side to qualify for the Round of 16.

Can the United States make a triumphant return to World Cup action? Will the Dragons make an unlikely run through Group B in their second World Cup appearance?

Let’s look at the current odds and the best bets for this encounter.

Odds for USA vs. Wales

  • USA (+150) | Draw (+220) | Wales (+195) are the three handicaps.
  • Draw No Bet: United States (-160) | Wales (+100)
  • Goals Over/Under: Over 2.5 (+130) | Under 2.5 (-190)

Unless otherwise specified, USA vs. Wales odds are current as of Monday, Oct. 24, at BetMGM Sportsbook.

The United States is the slight favorite in this group stage match, but only by a small margin. Both teams have roughly identical odds of making it to the Round of 16, hence both teams’ win value is positive.

Prediction: USA vs. Wales

  • Wales 2-1, USA

Manager Gregg Berhalter is entrusted with restoring the United States’ international relevance to this young and talented team. Berhalter has established himself as one of the finest managers in USMNT history since taking over in 2018.

Berhalter leads all managers in per-match statistics, with an average of 2.15 goals for and 0.64 goals against (minimum of 18 matches).

Overall, the Stars and Stripes are a far better team, led by captain Christian Pulisic. Wales will have their hands full with players like Brenden Aaronson, Giovanni Reyna, Tyler Adams, Weston McKennie, and DeAndre Yedlin.

The United States is also the league’s youngest team, with only a few players over the age of 30.

The Dragons don’t have many scoring alternatives aside from captain and star Gareth Bale up front. Apart from vice-captain Aaron Ramsey, Bale has scored more international goals (40) than the rest of the squad combined (33).

Wales will rely on young players Brennan Johnson and Daniel James.

For manager Rob Page, defense will be critical to remaining competitive in games. Page employs a consistent defense, which is led by defender Chris Gunter, who has 109 caps for Wales.

Wayne Hennessey, another long-serving Wales player, will start in goal.

This will be a competitive match, but the United States will pull away in the second half to win.

Betting Predictions for the United States vs. Wales

  • In an International Friendly in 2020, the United States and Wales tied 0-0.
  • In their first meeting, the United States defeated Wales 2-0 in 2003.
  • In the 2021 Gold Cup Final, the United States defeated Mexico 1-0.
  • Wales qualified for the World Cup after defeating Ukraine 1-0 in a playoff.
  • The United States qualified for six consecutive World Cups before falling short in 2018.
  • Wales last competed in the World Cup in 1958, finishing sixth.

Best Bets for the United States vs. Wales

BetMGM Sportsbook offers a moneyline of (+150) for the United States.


The Americans are a much better team overall, and these two moneylines should not be as close as they are. This is the best value for taking the USMNT straight up, as they should differentiate themselves as the match approaches.

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